An Inter digital- Poison Ivy Leaf Shaped Filtenna with Multiple Defects in Ground for S-Band bandwidth Applications

The proposed work, a filtenna for s band application is implemented. It is designed by embedding an Interdigital band pass filter (IDBPF) and leaf shaped antenna which are operated in S band. The IDFBPF is having seven resonators with one end shorted through dual vias. It offers a bandwidth of 1.3GHz from 1.65GHz to 2.95GHz.  A Dumbbell shaped DGS (Defected Ground Structure) provided in ground to improve the filter characteristics.  Measured pass (BRL) band return loss (S11) & insertion loss (S12) are -18dB & -4.6dB correspondingly. Further, leaf shaped antenna is designed based on modified polar transformation equation; it has 2.7 GHz bandwidth from 1.3 GH to 3 GHz and has a gain of -5.45dBi, and return loss (S11) of -19.5 dB. The filtenna is obtained by integrating the IDBBPF in the fodder line of the leaf designed antenna. The final model has 1.2 GHz operating bandwidth from 02.30 GHz to 03.50 GHz with peak arrival damages at 2.4GHz and 3.1GHz with -20dB and-24dB respectively. The designed filtenna has a pass band gain of -5.3dBi. The shift in operating band is due to combining the filter with antenna. The proposed model is invented on FR4 substrate having a wideness of 01.60 mm and having a dimension of 0.25 0.58 ?02. In this final model two complementary slip ring resonators (CSRR) are used in addition with four dumbbell structures as defects in the ground plane to avoid ripples in return loss (S11) graph. A high degree of concordance exists between empirically measured and simulated outcomes. The radiation band is showing its application in S band wireless mobile communications, Wi-Fi and ISM 2.4GHz band

EVALUATING RISK FACTORS, CLINICAL AND THERAPEUTIC PROFILE OF STROKE PATIENTS PRESENTING TO A TERTIARY CARE HOSPITAL

Objective: According to the World Health Organization, stroke is the second leading cause of death for people above the age of 60 years, and the fifth leading cause in people aged 15–59 years old. This study mainly aims to evaluate the prevalence of risk factors, clinical features, pattern of drugs prescribed, and severity of stroke among patients. Methods: A cross-sectional study was carried out in a tertiary care teaching hospital on 210 patients for a period of 6 months. Patients aged 18 years and above were included in the study. The severity of stroke was assessed using National Institute of Health Stroke Scale (NIHSS). Results: The majority of the patients were under the age group of 61–70 years (31%). The incidence of ischemic stroke (81%) was more common compared to hemorrhagic stroke (19%). Males (66%) are prone to stroke compared to females (34%). The most common risk factor was hyperlipidemia (29%) followed by hypertension (17%). Antihypertensives (28%) were most commonly used drugs followed by antihyperlipidemics (23%). Most of the prescriptions were prescribed with 4–6 drugs per prescription (62%). Moderate stroke (69%) was most commonly observed in patients. A total of 147 drug-drug interactions were observed. Among 147 drug-drug interaction, the most commonly observed drug-drug interaction was aspirin with metformin (15%). Conclusion: The present study emphasizes on the need to identify risk factors and providing awareness among the patients by a pharmacist in minimizing the disease burden. Early identification of risk factors and pattern of therapy based on therapeutic guidelines plays a crucial role in qualitative patient care

A CASE REPORT ON CHRONIC LEAD POISONING FROM OCCUPATIONAL EXPOSURE

The hazard to public health from lead continues to be a matter of concern. It is one of the most serious environmental poisons among the toxic heavy metals all over the world. Lead poisoning is seen in all age groups, especially in adults working in lead-based industries. We report the case of a 28-year-old man working in an unorganized lead-based manufacturing unit admitted with the complaints of giddiness, excessive tiredness, pain in the upper abdomen, decreased appetite, excessive body pains, increased sweating, and oliguria. Investigations carried out during the admission showed hemoglobin levels of 8.5 g/dl and blood lead level (BLL) of 115 μg/dl. The patient was subjected to chelation therapy. After repeated course of chelation therapy, he has shown the signs of improvement. The paucity of a safe workplace and awareness among workers results in high BLLs. Therefore, education and awareness related to lead hazards is considered necessary

SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL HETEROCYCLIC MANNICH BASES

Various novel heterocyclic mannich bases were prepared by using Mannich reaction. Acetanilide was treated with substituted benzaldehyde and morpholine / methyl amine to give corresponding titled compounds in good yields. The synthesized compounds were characterized by physical properties and spectral studies (IR, 1H-NMR) and tested for antimicrobial activity against Escherichia coli, Bacillus subtilis by using cup plate method with reference to the standard Streptomycin. All the titled compounds show good antimicrobial activity

COMPARISION OF EFFICACYAND SAFETY OF ORAL LABETALOL AND NIFEDIPINE IN PREECLAMPSIA: A PROSPECTIVE OBSERVATIONAL STUDY

Objective: To compare the efficacy and safety of oral Labetalol and Nifedipine in preeclampsia patients and to aid professionals in making appropriate therapeutic decisions in the management of preeclampsia.Methods: A Prospective observational study with the total of 152 pregnant women with preeclampsia is conducted in a Tertiary Care Hospital in India. Pregnant women with preeclampsia prescribed with either oral labetalol or oral nifedipine were selected. Main outcome measures include monitoring of adverse effects of labetalol and nifedipine and efficacy of both drugs. Blood pressures were measured every 4 hrs using sphygmomanometer and average of three consecutive readings is recorded. The two groups were followed until delivery and are interviewed for any adverse reactions.Results: The duration of days required for labetalol to normalize the high blood pressure is 5 days (5±2.63 d), and that of nifedipine is 7.5 days (7.5±3.83 d) with P value of 0.0015. Common adverse Drug reactions (ADR's) of the both drugs are pedal edema (50%, 47.36%), headache (44.7%, 26.31%), and orthostatic hypotension (9%, 7%) etc are compared.Conclusion: Oral Labetalol is more efficacious than Oral Nifedipine, with an exception of more adverse effects and high cost.Â

Formulation and evaluation of atenolol oro dispersable tablets by co-processed super-disintegration process

Oral disintegrating tablet (ODT) is defined as A solid dosage form containing medical substances or active ingredient which disintegrates rapidly usually within a matter of seconds when placed upon the tongue. The aim of the present research is to formulate Atenolol oral disintegrating tablets.Atenolol is ?1- cardio selective adrenergic receptor blocker, widely used in the treatment of hypertension, angina pectoris, arrhythmias and myocardial infarction. It works by slowing down the heart and reducing the work load of the heart.Atenolol was specifically developed so as to pass the blood brain barrier and overcome theside effects such as depression and nightmares.It has been reported that atenolol undergo extensive hepatic first pass metabolism following oral administration and has shorter biological half-life of 6 7 hours with oral bioavailability of 50%. The conventional tablets of atenolol are reported to exhibit fluctuations in the plasma drug levels after administration. Atenolol ODTs are prepared by novel co-processed super-disintegration process using Cross Povidone and Cross carmellose sodium, as the super disintegrants. The prepared tablets were characterized for their hardness, weight variation, disintegration time, wetting time, water absorption ratio friability, and in vitro dissolution studies.he ability of the tablet to release the drug faster depends on the concentration and type of super disintegrant. In this study the oral disintegrating tablets containing Cross carmellose sodium and Cross Povidone as the super disintegrant in the ratio of 1:1 shows better release of drug. About 99.5% of the drug was released from the tablets in 6 mins. Therefore, based on the physico chemical properties, in vitro drug release profile and mouth feel formulation F 1 containing 1:1 of Cross carmellose sodium and crospovidone is optimised as the best formulation

Simulation Based Predictive Analysis of Indian Airport Transportation System Using Computational Intelligence Techniques

Normally, flight delays and cancellations have significant impact on airlines operations and passenger’s satisfaction. Flight delays reduce the performance of airline operations and make significant effect on airports on time performance. Previously statistical models have been used for flight delays analysis. This study was applied in Indian aviation industry and it has given statistical analysis of domestic airlines. In this research paper, we have applied Machine Learning models with the help of computational intelligence techniques for predicting airport transport management system. We have also applied computational intelligence techniques such as Particle Swarm Optimization (PSO) and Ant Colonization Optimization (ACO) to optimize the prediction model for delay period time and calculating the most optimal dependability. We have made comprehensive analysis of Data Efficiency Model for different airlines with various approaches as well as comparative analysis of accuracy for predicting airport model by using various machine learning models. In this study we have presented invaluable insights for the analysis of flight delay models

Hydrodynamics of Annular Circulating Fluidised Bed Drier with Millet and Ragi Particle Mixture

275-279Millet and ragi particle mixture with the millet particles having average 2250 μm diam and density 1163.9 kg/m3and ragi particles average 1500 μm diam and density 1310.4 kg/m3, with the mass fraction 0.25 of millet particles and 0.75 of ragi particles were used to study the hydrodynamics of an annular circulating fluidised bed drier. Gap openings were varied from 12mm to 72mm and it was found that mass flux of solids remained constant for all air velocities greater than 4.05m/s and for gap openings greater than 56 mm. Dilute phase flow and dense slugging flow regime models were verified. A correction factor, K was incorporated for the dense slugging flow regime. The error in the use of the model for pressure drop calculation was 20 per cent